Hospital Incidence of Clostridium difficile Infection (CDI) as a Risk Factor for Hospital-Associated CDI

Use of Electronic Data to Identify Risk Factors Associated with Clostridium difficile Infection (CDI) and to Develop CDI Risk Scores

Are Patients with Prior Clostridium difficile Infection (CDI) a Potential Source of Transmission during Hospital Admissions?

set included WCC (< 4, 12–19.9, or ≥20 × 10/L), BUN≥11 mmol/L, serum albumin <25 g/L, heart rate > 90/minute, and respiratory rate >20/minute. A predictive score of min 0 and max 13 points was derived. A score ≥7 points was associated with 70% cases of cCDI, showed 68% sensitivity (95% CI, 55–80) in the derivation set and 70% (51–88) in the validation set, a specificity of 73% (69–76) and 76% (...

527Age-Related Changes in the Incidence of Community-Associated Clostridium Difficile Infection (CDI)

New advances in the treatment of Clostridium difficile infection (CDI)

Clostridium difficile infections (CDI) have increased in frequency throughout the world. In addition to an increase in frequency, recent CDI epidemics have been linked to a hypervirulent C. difficile strain resulting in greater severity of disease. Although most mild to moderate cases of CDI continue to respond to metronidazole or vancomycin, refractory and recurrent cases of CDI may require al...

Does empirical Clostridium difficile infection (CDI) therapy result in false-negative CDI diagnostic test results?

BACKGROUND Patients with suspected Clostridium difficile infection (CDI) often receive empirical therapy prior to collection of stool specimens for diagnostic testing. The likelihood that such empirical therapy might result in false-negative CDI test results is unknown. METHODS We conducted a prospective study of CDI patients to determine the time to conversion of CDI test results, including ...